Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUN_1663Ni-Fe hydrogenase, small subunit; Quinone-reactive Ni/Fe hydrogenase. (412 aa)    
Predicted Functional Partners:
SUN_1662
Ni-Fe hydrogenase, large subunit; Quinone-reactive Ni/Fe hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.995
SUN_1661
Quinone-reactive Ni/Fe hydrogenase, cytochrome b subunit.
 
 
 0.985
SUN_1653
Ni-Fe hydrogenase, large subunit; Quinone-reactive Ni/Fe hydrogenase.
 
 
 0.981
SUN_1664
Ni-Fe hydrogenase, large subunit HupV.
 
 
 0.972
SUN_1660
Hydrogenase formation/expression protease.
 
  
 0.953
SUN_1642
Hydrogenase formation/expression protease.
 
  
 0.835
SUN_1659
Hypothetical protein.
 
 
 
 0.777
SUN_1648
Hydrogenase expression/formation protein HupF/HypC.
 
 
 0.721
SUN_1658
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.687
SUN_1649
Hydrogenase accessory protein HypB.
 
  
 0.683
Your Current Organism:
Sulfurovum sp. NBC371
NCBI taxonomy Id: 387093
Other names: S. sp. NBC37-1, Sulfurovum sp. NBC37-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.