STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LVIS_0278Adenosine deaminase. (347 aa)    
Predicted Functional Partners:
LVIS_2142
5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase; Belongs to the 5'-nucleotidase family.
 
  
 0.928
LVIS_0040
5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase; Belongs to the 5'-nucleotidase family.
 
  
 0.923
LVIS_1816
Inosine-uridine nucleoside N-ribohydrolase.
 
 
 0.914
deoD
Purine-nucleoside phosphorylase.
    
 0.910
LVIS_0403
Inosine-uridine nucleoside N-ribohydrolase.
  
 
 0.908
LVIS_2188
Inosine-uridine nucleoside N-ribohydrolase.
 
 
 0.908
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.611
LVIS_1186
5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase; Belongs to the 5'-nucleotidase family.
    
 0.559
LVIS_0277
Site-specific recombinase XerD; Belongs to the 'phage' integrase family.
       0.501
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.422
Your Current Organism:
Lactobacillus brevis
NCBI taxonomy Id: 387344
Other names: L. brevis ATCC 367, Lactobacillus brevis ATCC 367, Lactobacillus brevis str. ATCC 367, Lactobacillus brevis strain ATCC 367
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