STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LVIS_0695Hypothetical protein. (102 aa)    
Predicted Functional Partners:
LVIS_0451
Hypothetical protein.
  
     0.706
mprF-2
Predicted integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.655
pepX
Xaa-Pro dipeptidyl-peptidase. Serine peptidase. MEROPS family S15; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
  
     0.648
LVIS_1632
Hypothetical protein.
  
     0.632
LVIS_1926
Nucleotide-binding protein, UspA family.
  
     0.619
LVIS_1762
Superfamily I DNA and RNA helicase.
  
     0.605
LVIS_1432
TPR repeat protein.
  
   
 0.568
LVIS_1886
Predicted multitransmembrane protein.
 
     0.557
LVIS_0685
Hypothetical protein.
 
     0.553
LVIS_0032
Hypothetical protein.
  
     0.552
Your Current Organism:
Lactobacillus brevis
NCBI taxonomy Id: 387344
Other names: L. brevis ATCC 367, Lactobacillus brevis ATCC 367, Lactobacillus brevis str. ATCC 367, Lactobacillus brevis strain ATCC 367
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.