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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdhCacetyl-CoA decarbonylase/synthase beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (520 aa)    
Predicted Functional Partners:
cdhE
acetyl-CoA decarbonylase/synthase gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
 
 
 0.999
cdhD
acetyl-CoA decarbonylase/synthase delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
 
 0.999
cdhA
acetyl-CoA decarbonylase/synthase alpha subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
 0.999
cdhB
acetyl-CoA decarbonylase/synthase epsilon subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.
 
 
 0.995
AGK61990.1
CO dehydrogenase maturation factor; PF01656:COG3640; PFAM: CobQ/CobB/MinD/ParAnucleotidebindingdomain; COG: CO dehydrogenase maturation factor.
 
  
 0.991
AGK61227.1
Carbon-monoxide dehydrogenase, catalytic subunit; PF03063:TIGR01702:COG1151; PFAM: Prismane/COdehydrogenasefamily; COG: 6Fe-6S prismane cluster-containing protein; TIGR: carbon-monoxide dehydrogenase, catalytic subunit.
  
  
 0.979
AGK60804.1
Formylmethanofuran dehydrogenase, subunit G; PF04060:COG1456; PFAM: PutativeFe-Scluster; COG: CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein).
 
  
 0.948
AGK60620.1
PF02007:TIGR01114:COG1962; PFAM: TetrahydromethanopterinS-methyltransferaseMtrHsubunit; COG: Tetrahydromethanopterin S-methyltransferase, subunit H; TIGR: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H.
  
  
  0.935
mer
Methylenetetrahydromethanopterin reductase; Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT; Belongs to the mer family.
 
  
 0.931
AGK60050.1
PF13247:COG1142; PFAM: 4Fe-4Sdiclusterdomain; COG: Fe-S-cluster-containing hydrogenase components 2.
  
 
 0.929
Your Current Organism:
Archaeoglobus sulfaticallidus
NCBI taxonomy Id: 387631
Other names: A. sulfaticallidus PM70-1, Archaeoglobus sp. PM70-1, Archaeoglobus sulfaticallidus PM70-1
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