Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
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Score
CRP_0803-isopropylmalate dehydratase large subunit. (456 aa)    
Predicted Functional Partners:
CRP_078
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.999
CRP_081
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 0.999
CRP_082
3-isopropylmalate dehydrogenase.
 
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.985
CRP_029
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
  
 0.924
CRP_083
Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.914
aroC
Chorismate synthase; Belongs to the chorismate synthase family.
  
  
 0.905
CRP_172
Branched-chain amino acid aminotransferase.
  
  
 0.862
CRP_127
Acetolactate synthase large subunit; Belongs to the TPP enzyme family.
  
  
 0.782
CRP_084
seryl-tRNA synthetase.
       0.761
Your Current Organism:
Carsonella ruddii PV
NCBI taxonomy Id: 387662
Other names: C. Carsonella ruddii PV, Candidatus Carsonella ruddii PV, Candidatus Carsonella ruddii str. PV, Candidatus Carsonella ruddii strain PV, Carsonella-Pv
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