STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES3Hes family bHLH transcription factor 3. (171 aa)    
Predicted Functional Partners:
FANCL
FA complementation group L.
    
  0.680
FANCG
FA complementation group G.
    
  0.680
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
  0.680
FANCF
FA complementation group F.
    
  0.680
FANCA
FA complementation group A.
    
  0.593
ENSGAGP00000028196
NTF2 domain-containing protein.
    
  0.593
NUTF2
Nuclear transport factor 2.
    
  0.593
RNF207
Ring finger protein 207.
    
 
 0.587
ENSGAGP00000003427
Uncharacterized protein.
    
  0.575
FANCE
FA complementation group E.
    
  0.575
Your Current Organism:
Gopherus agassizii
NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.