STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MANSC4MANSC domain containing 4. (347 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 
 0.775
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.757
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.757
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.729
BIN3
Bridging integrator 3.
    
 
 0.636
BIN1
Bridging integrator 1.
    
 
 0.636
BIN2
Bridging integrator 2.
    
 
 0.636
AMPH
Amphiphysin.
    
 
 0.636
AAK1
AP2 associated kinase 1.
    
 
 0.625
BMP2K
BMP2 inducible kinase.
    
 
 0.625
Your Current Organism:
Gopherus agassizii
NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.