STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSGAGP00000026114SERPIN domain-containing protein; Belongs to the serpin family. (379 aa)    
Predicted Functional Partners:
ENSGAGP00000014438
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 0.803
HGFAC
HGF activator.
  
 0.674
PROC
Protein C, inactivator of coagulation factors Va and VIIIa.
  
 0.673
PLAT
Plasminogen activator, tissue type.
   
 0.655
ENSGAGP00000036151
Uncharacterized protein.
   
 0.654
ENSGAGP00000022669
Uncharacterized protein; Belongs to the peptidase C1 family.
   
 0.626
ENSGAGP00000001588
Uncharacterized protein.
  
  0.600
ENSGAGP00000010525
Uncharacterized protein.
  
  0.600
ENSGAGP00000010535
Uncharacterized protein.
  
  0.600
F7
Coagulation factor VII.
  
  0.600
Your Current Organism:
Gopherus agassizii
NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise
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