CD40LG protein (Gopherus agassizii) - STRING interaction network

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CD40LG

CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)

Predicted Functional Partners:

ENSGAGP00000025784

0.994

ICOS

0.940

ENSGAGP00000026769

0.935

FASLG

0.902

ENSGAGP00000002404

0.880

TNC

0.880

TNFRSF11B

0.880

ENSGAGP00000029155

0.880

ENSGAGP00000029158

0.880

FAS

0.878

Your Current Organism:

Gopherus agassizii

NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40LG	ENSGAGP00000002404	ENSGAGP00000029037	ENSGAGP00000002404	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.880
CD40LG	ENSGAGP00000025784	ENSGAGP00000029037	ENSGAGP00000025784	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNFR-Cys domain-containing protein.	0.994
CD40LG	ENSGAGP00000026769	ENSGAGP00000029037	ENSGAGP00000026769	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNFR-Cys domain-containing protein.	0.935
CD40LG	ENSGAGP00000029155	ENSGAGP00000029037	ENSGAGP00000029155	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNFR-Cys domain-containing protein.	0.880
CD40LG	ENSGAGP00000029158	ENSGAGP00000029037	ENSGAGP00000029158	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.880
CD40LG	FAS	ENSGAGP00000029037	ENSGAGP00000029103	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Fas cell surface death receptor.	0.878
CD40LG	FASLG	ENSGAGP00000029037	ENSGAGP00000031690	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Fas ligand; Belongs to the tumor necrosis factor family.	0.902
CD40LG	ICOS	ENSGAGP00000029037	ENSGAGP00000019264	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Inducible T cell costimulator.	0.940
CD40LG	TNC	ENSGAGP00000029037	ENSGAGP00000015285	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tenascin C.	0.880
CD40LG	TNFRSF11B	ENSGAGP00000029037	ENSGAGP00000027711	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.	0.880
ENSGAGP00000002404	CD40LG	ENSGAGP00000002404	ENSGAGP00000029037	Uncharacterized protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.880
ENSGAGP00000025784	CD40LG	ENSGAGP00000025784	ENSGAGP00000029037	TNFR-Cys domain-containing protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.994
ENSGAGP00000025784	FAS	ENSGAGP00000025784	ENSGAGP00000029103	TNFR-Cys domain-containing protein.	Fas cell surface death receptor.	0.508
ENSGAGP00000025784	FASLG	ENSGAGP00000025784	ENSGAGP00000031690	TNFR-Cys domain-containing protein.	Fas ligand; Belongs to the tumor necrosis factor family.	0.684
ENSGAGP00000025784	ICOS	ENSGAGP00000025784	ENSGAGP00000019264	TNFR-Cys domain-containing protein.	Inducible T cell costimulator.	0.581
ENSGAGP00000026769	CD40LG	ENSGAGP00000026769	ENSGAGP00000029037	TNFR-Cys domain-containing protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.935
ENSGAGP00000026769	FASLG	ENSGAGP00000026769	ENSGAGP00000031690	TNFR-Cys domain-containing protein.	Fas ligand; Belongs to the tumor necrosis factor family.	0.996
ENSGAGP00000026769	TNFRSF11B	ENSGAGP00000026769	ENSGAGP00000027711	TNFR-Cys domain-containing protein.	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.	0.775
ENSGAGP00000029155	CD40LG	ENSGAGP00000029155	ENSGAGP00000029037	TNFR-Cys domain-containing protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.880
ENSGAGP00000029158	CD40LG	ENSGAGP00000029158	ENSGAGP00000029037	Uncharacterized protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.880

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