STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G7J5C4_MEDTREukaryotic DNA topoisomerase I, catalytic core protein. (270 aa)    
Predicted Functional Partners:
G7KVX8_MEDTR
Tyrosyl-DNA phosphodiesterase.
    
 
 0.835
G7JKW4_MEDTR
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 
 0.711
B7FGV0_MEDTR
Putative aminoacyltransferase, E1 ubiquitin-activating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.697
G7K599_MEDTR
Putative aminoacyltransferase, E1 ubiquitin-activating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.697
A0A072UZI8
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 
 0.668
A0A072TLS9
Putative lipid-A-disaccharide synthase.
    
 
 0.647
A0A072W210
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
    
 
 0.647
G7J1L2_MEDTR
Crossover junction endonuclease MUS81-like protein.
    
 
 0.614
G7IDV7_MEDTR
Timeless protein carboxy-terminal region protein.
    
 
 0.575
G7I6T9_MEDTR
RNA-binding (RRM/RBD/RNP motif) family protein.
   
   0.563
Your Current Organism:
Medicago truncatula
NCBI taxonomy Id: 3880
Other names: M. truncatula, Medicago truncatula Gaertn., barrel medic
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.