STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G7JY17_MEDTRDihydropterin pyrophosphokinase/dihydropteroate synthase. (515 aa)    
Predicted Functional Partners:
A0A072UEP1
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.998
A0A072V9A4
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
 
 0.977
A0A072VFR4
Tetrahydrofolylpolyglutamate synthase.
  
 
 0.977
A0A072VHI5
Folylpolyglutamate synthase.
  
 
 0.977
G7J9Z6_MEDTR
Folylpolyglutamate synthase.
  
 
 0.977
G7K218_MEDTR
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
  
 
 0.977
G7L1S8_MEDTR
Tetrahydrofolylpolyglutamate synthase.
  
 
 0.977
A0A072VQ91
Branched-chain-amino-acid aminotransferase-like protein.
  
 
 0.973
I3SQ86_MEDTR
Putative D-amino-acid transaminase, Aminodeoxychorismate lyase.
  
 
 0.969
A0A072TL11
Putative GTP cyclohydrolase I.
  
 
 0.918
Your Current Organism:
Medicago truncatula
NCBI taxonomy Id: 3880
Other names: M. truncatula, Medicago truncatula Gaertn., barrel medic
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.