STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM84376.12-dehydro-3-deoxygluconokinase. (341 aa)    
Predicted Functional Partners:
SHM84328.1
2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase.
 
 
 0.977
SHN30515.1
2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase.
 
 
 0.951
SHM75227.1
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
  0.834
SHM69988.1
Altronate hydrolase.
 
 
 0.820
SHM73482.1
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
  0.803
uxuA-2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
  0.801
SHM84354.1
YhcH/YjgK/YiaL family protein.
 
     0.801
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
  0.798
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.745
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.704
Your Current Organism:
Cyclobacterium lianum
NCBI taxonomy Id: 388280
Other names: C. lianum, CGMCC 1.6102, Cyclobacterium lianum Ying et al. 2006, JCM 14011, strain HY9
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.