node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTQ76228.1 | dme | LAX5112_04528 | LAX5112_02424 | Indolepyruvate ferredoxin oxidoreductase. | NAD-dependent malic enzyme. | 0.955 |
CTQ76228.1 | ilvH | LAX5112_04528 | LAX5112_02659 | Indolepyruvate ferredoxin oxidoreductase. | Acetolactate synthase small subunit. | 0.833 |
CTQ76228.1 | leuA_1 | LAX5112_04528 | LAX5112_00939 | Indolepyruvate ferredoxin oxidoreductase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.846 |
CTQ76228.1 | leuA_2 | LAX5112_04528 | LAX5112_01612 | Indolepyruvate ferredoxin oxidoreductase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.852 |
CTQ76228.1 | leuB_1 | LAX5112_04528 | LAX5112_03979 | Indolepyruvate ferredoxin oxidoreductase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.745 |
CTQ76228.1 | leuD_2 | LAX5112_04528 | LAX5112_04328 | Indolepyruvate ferredoxin oxidoreductase. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.774 |
CTQ76228.1 | tme | LAX5112_04528 | LAX5112_03798 | Indolepyruvate ferredoxin oxidoreductase. | NADP-dependent malic enzyme. | 0.949 |
CTQ76228.1 | xsc_1 | LAX5112_04528 | LAX5112_00374 | Indolepyruvate ferredoxin oxidoreductase. | Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. | 0.631 |
dme | CTQ76228.1 | LAX5112_02424 | LAX5112_04528 | NAD-dependent malic enzyme. | Indolepyruvate ferredoxin oxidoreductase. | 0.955 |
dme | ilvC | LAX5112_02424 | LAX5112_01599 | NAD-dependent malic enzyme. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.495 |
dme | ilvD | LAX5112_02424 | LAX5112_02887 | NAD-dependent malic enzyme. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.419 |
dme | ilvH | LAX5112_02424 | LAX5112_02659 | NAD-dependent malic enzyme. | Acetolactate synthase small subunit. | 0.848 |
dme | leuA_1 | LAX5112_02424 | LAX5112_00939 | NAD-dependent malic enzyme. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.794 |
dme | leuA_2 | LAX5112_02424 | LAX5112_01612 | NAD-dependent malic enzyme. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.794 |
dme | leuB_1 | LAX5112_02424 | LAX5112_03979 | NAD-dependent malic enzyme. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.454 |
dme | leuD_2 | LAX5112_02424 | LAX5112_04328 | NAD-dependent malic enzyme. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.716 |
dme | tme | LAX5112_02424 | LAX5112_03798 | NAD-dependent malic enzyme. | NADP-dependent malic enzyme. | 0.855 |
dme | xsc_1 | LAX5112_02424 | LAX5112_00374 | NAD-dependent malic enzyme. | Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. | 0.717 |
ilvC | dme | LAX5112_01599 | LAX5112_02424 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | NAD-dependent malic enzyme. | 0.495 |
ilvC | ilvD | LAX5112_01599 | LAX5112_02887 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.990 |