STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (312 aa)    
Predicted Functional Partners:
EAZ80258.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 0.994
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.994
EAZ81889.1
uroporphyrinogen-III C-methyltransferase.
 
 0.989
EAZ82240.1
uroporphyrinogen-III C-methyltransferase.
 
 0.988
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 0.987
EAZ81471.1
uroporphyrinogen-III synthase.
  
 0.987
hemL
Glutamate-1-semialdehyde-2,1-aminomutase.
  
 0.947
EAZ80292.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type.
 
  
 0.891
EAZ82383.1
NifU domain protein.
 
      0.878
EAZ82241.1
Siroheme synthase.
 
 
 0.822
Your Current Organism:
Algoriphagus machipongonensis
NCBI taxonomy Id: 388413
Other names: A. machipongonensis, ATCC BAA-2233, Algoriphagus machipongonensis Alegado et al. 2013, Algoriphagus sp. PR1, DSM 24695, strain PR1
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