node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAZ81355.1 | EAZ82605.1 | ALPR1_20003 | ALPR1_10330 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.828 |
EAZ81355.1 | EAZ82606.1 | ALPR1_20003 | ALPR1_10335 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Pyrazinamidase/nicotinamidase (PZAase)(Nicotine deamidase) (NAMase). | 0.802 |
EAZ81355.1 | cobB | ALPR1_20003 | ALPR1_10100 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.811 |
EAZ81355.1 | nadD | ALPR1_20003 | ALPR1_19793 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.467 |
EAZ81355.1 | surE | ALPR1_20003 | ALPR1_14299 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.798 |
EAZ81699.1 | EAZ82605.1 | ALPR1_00620 | ALPR1_10330 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.895 |
EAZ81699.1 | EAZ83237.1 | ALPR1_00620 | ALPR1_13490 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.886 |
EAZ81699.1 | nadD | ALPR1_00620 | ALPR1_19793 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.920 |
EAZ81699.1 | nadE | ALPR1_00620 | ALPR1_15114 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.489 |
EAZ81699.1 | surE | ALPR1_00620 | ALPR1_14299 | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.802 |
EAZ82058.1 | EAZ82605.1 | ALPR1_02415 | ALPR1_10330 | Hydroperoxide resistance protein OsmC. | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.652 |
EAZ82605.1 | EAZ81355.1 | ALPR1_10330 | ALPR1_20003 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.828 |
EAZ82605.1 | EAZ81699.1 | ALPR1_10330 | ALPR1_00620 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide diphosphorylase (carboxylating); Belongs to the NadC/ModD family. | 0.895 |
EAZ82605.1 | EAZ82058.1 | ALPR1_10330 | ALPR1_02415 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hydroperoxide resistance protein OsmC. | 0.652 |
EAZ82605.1 | EAZ82606.1 | ALPR1_10330 | ALPR1_10335 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Pyrazinamidase/nicotinamidase (PZAase)(Nicotine deamidase) (NAMase). | 0.999 |
EAZ82605.1 | EAZ82607.1 | ALPR1_10330 | ALPR1_10340 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein. | 0.778 |
EAZ82605.1 | EAZ83237.1 | ALPR1_10330 | ALPR1_13490 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.890 |
EAZ82605.1 | cobB | ALPR1_10330 | ALPR1_10100 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily. | 0.642 |
EAZ82605.1 | nadD | ALPR1_10330 | ALPR1_19793 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.932 |
EAZ82605.1 | nadE | ALPR1_10330 | ALPR1_15114 | Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.745 |