STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (303 aa)    
Predicted Functional Partners:
menG
Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
    
 0.896
EAZ80032.1
Thioesterase family protein.
 
  
 0.878
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.829
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.823
EAZ80033.1
Putative isochorismate synthase.
 
   
 0.797
EAZ79577.1
O-succinylbenzoic acid--CoA ligase.
 
   
 0.773
argS
arginine--tRNA ligase.
       0.767
EAZ83220.1
Glutathione peroxidase family protein; Belongs to the glutathione peroxidase family.
       0.759
EAZ79745.1
Mandelate racemase/muconate lactonizing enzyme family protein.
 
   
 0.752
EAZ79462.1
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
    
 0.678
Your Current Organism:
Algoriphagus machipongonensis
NCBI taxonomy Id: 388413
Other names: A. machipongonensis, ATCC BAA-2233, Algoriphagus machipongonensis Alegado et al. 2013, Algoriphagus sp. PR1, DSM 24695, strain PR1
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