Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
divICCell division protein DivIC, putative; GC: 38.48%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.823. Curator(s): J. Alves; Protein involved in cell cycle and cell division. (122 aa)    
Predicted Functional Partners:
divIB
Cell division protein DivIB, putative; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
 
 
 0.943
SSA_0009
Ribosome-associated heat shock protein (S4), putative; GC: 38.58%; Codon Adaptation Index (CAI): 0.771. Curator(s): J. Alves; Protein involved in RNA binding.
  
    0.861
SSA_0012
Beta-lactamase class A, putative; GC: 37.54%; Codon Adaptation Index (CAI): 0.812. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.979); Curator(s): J. Alves.
 
     0.851
ftsW
Cell division protein FtsW, putative; GC: 44.2%; Transporter classification TC:9.B.3.1.3. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.729. SignalP prediction: Yes (prob. 0.95); Protein involved in cell division; Belongs to the SEDS family.
 
 
 
 0.845
rodA
Rod shape determining protein (cell-cycle protein), putative; GC: 44.77%; Transporter classification TC:9.B.3.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.775. Curator(s): L. Ozaki, J. Alves; Protein involved in cell division; Belongs to the SEDS family.
   
 
 0.760
mesJ
Cell cycle control ATPase, PP-loop superfamily, putative; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
    0.759
pbpX
Penicillin-binding protein 2X, putative; GC: 45.35%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.791. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.924); Protein involved in cell division and cell wall biosynthesis (sensu Bacteria).
 
 
 0.752
pth
Peptidyl-tRNA hydrolase, putative; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.745
trcF
Transcription-repair coupling factor, putative; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
    0.738
hpt
Hypoxanthine guanine phosphoribosyltransferase, putative; GC: 32.79%; Codon Adaptation Index (CAI): 0.846. Curator(s): J. Alves; Protein involved in metal ion binding; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.709
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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