close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
divICCell division protein DivIC, putative; GC: 38.48%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.823. Curator(s): J. Alves; Protein involved in cell cycle and cell division. (122 aa)    
Predicted Functional Partners:
divIB
Cell division protein DivIB, putative; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
 
 
 0.992
SSA_0009
Ribosome-associated heat shock protein (S4), putative; GC: 38.58%; Codon Adaptation Index (CAI): 0.771. Curator(s): J. Alves; Protein involved in RNA binding.
  
    0.806
SSA_0012
Beta-lactamase class A, putative; GC: 37.54%; Codon Adaptation Index (CAI): 0.812. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.979); Curator(s): J. Alves.
 
     0.776
mur2
Peptidoglycan hydrolase, putative; GC: 41.63%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.815. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in hydrolase activity.
  
   
 0.716
mesJ
Cell cycle control ATPase, PP-loop superfamily, putative; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
    0.633
pth
Peptidyl-tRNA hydrolase, putative; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.608
trcF
Transcription-repair coupling factor, putative; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
    0.603
adcB
ABC transporter (permease), Zn porter, putative; GC: 45.23%; Transporter classification TC:3.A.1.15.3. Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.727. Curator(s): M. Serrano; Protein involved in ATPase activity, coupled to transmembrane movement of substances.
      
 0.601
SSA_0324
Conserved uncharacterized protein; GC: 46.87%; Codon Adaptation Index (CAI): 0.852. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in regulation of transcription, DNA-dependent.
  
     0.598
hpt
Hypoxanthine guanine phosphoribosyltransferase, putative; GC: 32.79%; Codon Adaptation Index (CAI): 0.846. Curator(s): J. Alves; Protein involved in metal ion binding; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.561
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (44%) [HD]