STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacD-2Tagatose 1,6-diphosphate aldolase, putative; GC: 50.19%; Codon Adaptation Index (CAI): 0.765. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in lactose catabolism via tagatose-6-phosphate; Belongs to the aldolase LacD family. (345 aa)    
Predicted Functional Partners:
lacC
Tagatose-6-phosphate kinase, putative; GC: 41.72%; Codon Adaptation Index (CAI): 0.773. Curator(s): J. Alves; Protein involved in lactose catabolism via tagatose-6-phosphate; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.971
agaS
Tagatose-6-phosphate ketose/aldose isomerase, putative; GC: 49.79%; Codon Adaptation Index (CAI): 0.771. Curator(s): J. Alves.
 
     0.904
pfk
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.904
lacD
Tagatose 1,6-diphosphate aldolase 2, putative; GC: 45.97%; Codon Adaptation Index (CAI): 0.791; Belongs to the aldolase LacD family.
  
  
 
0.902
lacE
Phosphotransferase system lactose-specific component IIBC, putative; GC: 45.28%; Transporter classification TC:4.A.3.1.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.776. Curator(s): J. Alves.
 
  
 0.899
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, putative; GC: 46.39%; Codon Adaptation Index (CAI): 0.791. Curator(s): X. Ge; Protein involved in oxidoreductase activity; Belongs to the aldehyde dehydrogenase family.
   
 
  0.824
galM
Aldose 1-epimerase, putative; Converts alpha-aldose to the beta-anomer.
  
  
 0.788
lacG
Phospho-B-galactosidase LacG, putative; GC: 42.79%; Codon Adaptation Index (CAI): 0.786. LipoP prediction: SpI; Protein involved in lactose catabolism via tagatose-6-phosphate; Belongs to the glycosyl hydrolase 1 family.
  
  
 0.761
SSA_0055
PTS system, IIC component, putative; GC: 45.14%; Transporter classification TC:4.A.6.1.2. Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.767. Curator(s): J. Alves.
 
    0.721
lacF
PTS system, lactose-specific IIA component, putative; GC: 44.34%; Transporter classification TC:4.A.3.1.1. Codon Adaptation Index (CAI): 0.761.
  
  
 0.676
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.