Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_0067Acyltransferase (yrhL-like subfamily of SGNH-hydrolases), putative; GC: 45.96%; Transmembrane domains: 12. Codon Adaptation Index (CAI): 0.782. Curator(s): J. Alves; Protein involved in transferase activity, transferring groups other than amino-acyl groups. (601 aa)    
Predicted Functional Partners:
SSA_0066
Conserved hypothetical protein; GC: 44.2%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.79. Curator(s): J. Alves.
 
     0.931
SSA_0065
Low molecular weight phosphotyrosine protein phosphatase, putative; GC: 44.68%; Codon Adaptation Index (CAI): 0.79. Curator(s): J. Alves; Protein involved in protein amino acid dephosphorylation; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
    0.855
ruvB
Holliday junction DNA helicase ruvB, putative; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.675
adhE
Alcohol-acetaldehyde dehydrogenase, putative; GC: 45.69%; Codon Adaptation Index (CAI): 0.794. Curator(s): J. Alves; Protein involved in oxidoreductase activity; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
       0.656
SSA_0064
Conserved hypothetical protein; GC: 45.44%; Codon Adaptation Index (CAI): 0.79. Curator(s): J. Alves.
       0.447
dltA
D-alanine--D-alanyl carrier protein ligase, putative; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs [...]
  
   
 0.422
SSA_1651
Conserved hypothetical protein; GC: 45.69%; Codon Adaptation Index (CAI): 0.775.
  
     0.419
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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