STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nanEN-acetylmannosamine-6-p hosphate 2-epimerase 1, putative; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (232 aa)    
Predicted Functional Partners:
nagA
N-acetylglucosamine-6-phosphate deacetylase, putative; GC: 48.7%; Codon Adaptation Index (CAI): 0.786; Protein involved in hydrolase activity.
 
  
 0.971
glk
ROK family protein, putative; GC: 46.67%; Codon Adaptation Index (CAI): 0.804. Curator(s): J. Alves; Protein involved in transferase activity and kinase activity.
 
 0.927
nagB
Glucosamine-6-phosphate deaminase, putative; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 
   
 0.859
glmU
N-acetylglucosamine-1-phosphate uridyltransferase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repea [...]
     
 0.823
SSA_0073
Conserved hypothetical protein; GC: 31.13%; Codon Adaptation Index (CAI): 0.778. Curator(s): J. Alves; Protein involved in molecular function unknown.
 
  
 0.822
rmlA
Glucose-1-phosphate thymidylytransferase, putative; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
     
  0.800
galU
Glucose-1-phosphate uridylyltransferase, putative; GC: 45.83%; Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.993); Helix-turn-helix prediction: AraC; Protein involved in nucleotidyltransferase activity.
     
  0.800
SSA_0078
N-acetylneuraminate lyase, putative; GC: 46.51%; Codon Adaptation Index (CAI): 0.782. Curator(s): J. Alves; Protein involved in lyase activity.
 
  
 0.790
SSA_0081
Transcriptional regulator, RpiR family (phosphosugar-binding), putative; GC: 42.72%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.765. Curator(s): J. Alves; Protein involved in regulation of transcription, DNA-dependent.
 
   
 0.774
SSA_0072
ABC sugar transporter, MsmK-like protein, putative; GC: 42.5%; Transporter classification TC:3.A.1.1.2. Codon Adaptation Index (CAI): 0.776. Curator(s): J. Alves; Protein involved in nucleoside-triphosphatase activity; Belongs to the ABC transporter superfamily.
       0.741
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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