Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ntpIV-type sodium ATPase, subunit I, putative; GC: 49.69%; Transporter classification TC:3.A.2.2.2. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.765. Curator(s): J. Alves; Protein involved in hydrolase activity; Belongs to the V-ATPase 116 kDa subunit family. (651 aa)    
Predicted Functional Partners:
ntpK
V-type sodium ATPase, subunit K, putative; GC: 48.33%; Transporter classification TC:3.A.2.2.2. Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.755. SignalP prediction: Yes (prob. 0.96); Curator(s): J. Alves; Protein involved in hydrogen-transporting ATPase activity, rotational mechanism; Belongs to the V-ATPase proteolipid subunit family.
 
 0.999
ntpC
V-type sodium ATPase, subunit C, putative; GC: 50%; Transporter classification TC:3.A.2.2.2. Codon Adaptation Index (CAI): 0.77. Curator(s): J. Alves; Protein involved in hydrogen-transporting ATPase activity, rotational mechanism and hydrolase activity.
 
 0.999
ntpG
V-type sodium ATPase, subunit F, putative; GC: 48.91%; Transporter classification TC:3.A.2.2.2. Codon Adaptation Index (CAI): 0.787. Curator(s): J. Alves; Protein involved in hydrogen-transporting ATPase activity, rotational mechanism and hydrolase activity.
 
 0.999
ntpA
V-type sodium ATPase, subunit A, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
 
 0.999
ntpB
V-type sodium ATPase, subunit B, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
 
 0.999
ntpD
V-type sodium ATPase, subunit D, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
ntpE
V-type sodium ATPase, subunit E, putative; GC: 49.75%; Codon Adaptation Index (CAI): 0.772. Curator(s): J. Alves; Protein involved in hydrolase activity.
 
 0.998
uncE
Proton-translocating ATPase, F0 sector, subunit c, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.971
ppx
Inorganic pyrophosphatase/exopolyphosphatase, putative; GC: 44.02%; Codon Adaptation Index (CAI): 0.805. Curator(s): J. Alves.
     
  0.900
SSA_0083
Hypothetical protein; GC: 49.07%; Codon Adaptation Index (CAI): 0.75. Helix-turn-helix prediction: AraC. Curator(s): J. Alves.
       0.855
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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