Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
norNMulti antimicrobial extrusion (MATE) family transporter, putative; GC: 51.64%; Transporter classification TC:2.A.66.1.10. Transmembrane domains: 11. Codon Adaptation Index (CAI): 0.747. Curator(s): J. Alves. (425 aa)    
Predicted Functional Partners:
SSA_0098
Hydrolase, haloacid dehalogenase-like family, putative; GC: 45.85%; Codon Adaptation Index (CAI): 0.744. Curator(s): J. Alves; Protein involved in hydrolase activity.
   
   0.861
thrC
Threonine synthase, putative; GC: 48.28%; Codon Adaptation Index (CAI): 0.77. Curator(s): J. Alves; Protein involved in threonine biosynthesis.
       0.719
SSA_0094
Cell wall metabolism, LysM type protein, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.791. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves; Protein involved in cell wall catabolism.
       0.569
rplW
50S ribosomal protein L23, putative; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
   0.545
rplD
50S ribosomal protein L4, putative; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
   0.514
gapA
Glyceraldehyde 3-phosphate dehydrogenase, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.806; Protein involved in NAD binding; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.510
rpsA
30S ribosomal protein S1, putative; GC: 42.7%; Codon Adaptation Index (CAI): 0.82; Protein involved in protein biosynthesis.
   
    0.506
rplB
50S ribosomal protein L2, putative; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
   0.499
adhE
Alcohol-acetaldehyde dehydrogenase, putative; GC: 45.69%; Codon Adaptation Index (CAI): 0.794. Curator(s): J. Alves; Protein involved in oxidoreductase activity; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
    0.432
rpsQ
30S ribosomal protein S17, putative; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.416
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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