STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0103Integral membrane protein, putative; GC: 42.28%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.727. SignalP prediction: Yes (prob. 0.47); Curator(s): M. Serrano. (286 aa)    
Predicted Functional Partners:
tgt
Queuine tRNA-ribosyltransferase, putative; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose [...]
       0.723
SSA_0105
Uridine kinase, putative; GC: 47.26%; Codon Adaptation Index (CAI): 0.723. Curator(s): M. Serrano; Protein involved in transferase activity.
       0.548
dnaB
Replication initiation/membrane attachment protein DnaB, putative; GC: 30.63%; Codon Adaptation Index (CAI): 0.786. Curator(s): J. Alves.
 
     0.498
SSA_1076
Conserved hypothetical protein; GC: 44.94%; Codon Adaptation Index (CAI): 0.778; Protein involved in hydrolase activity and fatty acid biosynthesis.
  
     0.452
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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