STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ctpACopper-translocating P-type ATPase, putative; GC: 47.93%; Transporter classification TC:3.A.3.5.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.753. LipoP prediction: SpI. Helix-turn-helix prediction: AraC. Curator(s): M. Serrano; Protein involved in metal ion transporter activity. (748 aa)    
Predicted Functional Partners:
SSA_0141
Copper chaperone, putative; GC: 43.84%; Codon Adaptation Index (CAI): 0.758. Curator(s): M. Serrano; Protein involved in metal ion binding.
  
 
 0.956
SSA_0139
Copper transport operon or penicillinase transcriptional repressor, putative; GC: 45.27%; Codon Adaptation Index (CAI): 0.756. Curator(s): M. Serrano, J. Alves; Protein involved in specific transcriptional repressor activity.
  
  
 0.946
copA
P-type ATPase-metal/cation transport (probably copper), putative; GC: 37.4%; Transporter classification TC:3.A.3.5.1. Codon Adaptation Index (CAI): 0.768.
 
 
0.801
adcA
Zn-binding lipoprotein, putative; GC: 43.58%; Transporter classification TC:3.A.1.15.3. Codon Adaptation Index (CAI): 0.806. LipoP prediction: SpII. SignalP prediction: Yes (prob. 0.998); Curator(s): M. Serrano; Protein involved in establishment of competence for transformation; Belongs to the bacterial solute-binding protein 9 family.
     
 0.753
ppiA
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, putative; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
   0.732
SSA_0816
Copper transport operon or penicillinase transcription repressor, putative; GC: 45.24%; Codon Adaptation Index (CAI): 0.787. Curator(s): X. Ge, J. Alves; Protein involved in specific transcriptional repressor activity.
  
  
 0.709
dps
DNA Protection System, DNA-binding ferritin-like protein (oxidative damage protectant), putative; GC: 42.25%; Codon Adaptation Index (CAI): 0.828. Curator(s): P. Xu, J. Alves; Protein involved in ferric iron binding and response to stress; Belongs to the Dps family.
  
  
 0.639
czcD
Cation (Co/Zn/Cd) efflux protein, putative; GC: 45.78%; Transporter classification TC:2.A.4.1.3. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.773. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.997); Curator(s): J. Alves.
  
  
 0.631
nrdH
Glutaredoxin-like protein, putative; GC: 39.27%; Codon Adaptation Index (CAI): 0.804. Involved in electron transport system for ribonucleotide reductase system NrdEF. Curator(s): X. Ge; Protein involved in cell redox homeostasis.
   
 
 0.615
adcC
ABC transporter, Zn porter, putative; GC: 44.44%; Transporter classification TC:3.A.1.15.3. Codon Adaptation Index (CAI): 0.809. Curator(s): M. Serrano; Protein involved in nucleoside-triphosphatase activity and establishment of competence for transformation.
     
 0.608
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.