Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_0152Conserved hypothetical protein; GC: 42.87%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.786. Curator(s): M. Serrano, J. Alves. (950 aa)    
Predicted Functional Partners:
SSA_0151
Hypothetical protein; GC: 40.87%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.79. Curator(s): M. Serrano.
       0.773
SSA_0153
Hypothetical protein; GC: 42.7%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.737. Curator(s): M. Serrano.
       0.689
topA
DNA topoisomerase I, putative; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removin [...]
     
 0.510
SSA_0150
Hypothetical protein; GC: 43.23%; Codon Adaptation Index (CAI): 0.777. Curator(s): M. Serrano.
       0.440
SSA_0159
Conserved hypothetical protein; GC: 40.92%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.785. Curator(s): M. Serrano, J. Alves.
     
 0.438
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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