STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tyrSTyrosyl-tRNA synthetase 1, putative; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (419 aa)    
Predicted Functional Partners:
leuS
Leucyl-tRNA synthetase, putative; GC: 48.49%; Codon Adaptation Index (CAI): 0.791. Curator(s): P. Manque; Protein involved in leucyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.865
pheT
Phenylalanyl-tRNA synthetase beta chain, putative; GC: 47.55%; Codon Adaptation Index (CAI): 0.791. Curator(s): T. Kitten; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.859
argS
Arginyl-tRNA synthetase, putative; GC: 47.42%; Codon Adaptation Index (CAI): 0.766.
  
  
 0.841
metS
Methionyl-tRNA synthetase, putative; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
 
 0.829
hisS
Histidyl-tRNA synthetase, putative; GC: 47.23%; Codon Adaptation Index (CAI): 0.785; Protein involved in histidyl-tRNA aminoacylation.
  
 
 0.772
thrS
Threonyl-tRNA synthetase, putative; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
  
 
 0.755
ileS
Isoleucyl-tRNA synthetase, putative; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
  
 0.745
serS
Seryl-tRNA synthetase, putative; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
  
 0.737
valS
Valyl-tRNA synthetase, putative; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
  
 0.725
rrmA
23S rRNA m1G745 methyltransferase, putative; GC: 42.62%; Codon Adaptation Index (CAI): 0.774. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.57); Curator(s): M. Serrano; Protein involved in transferase activity.
       0.720
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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