STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nisKNisK (sensor-receptor histidine kinase domain), putative; GC: 42.58%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.784. Curator(s): P. Manque, J. Alves; Protein involved in transferase activity, kinase activity and transferase activity, transferring phosphorus-containing groups. (345 aa)    
Predicted Functional Partners:
nisR
Nisin biosynthesis two-component response transcriptional regulator nisR, putative; GC: 44.35%; Codon Adaptation Index (CAI): 0.765. Curator(s): P. Manque, J. Alves; Protein involved in sensory perception.
 
 0.998
SSA_1113
Two-component system, OmpR family, response regulator SaeR; GC: 41.2%; Codon Adaptation Index (CAI): 0.77. Curator(s): J. Alves; Protein involved in sensory perception.
 
 
 0.878
acoL
Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding.
    
 0.871
SSA_0202
Conserved hypothetical protein; GC: 46.51%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.752. Curator(s): P. Manque, J. Alves; possible transmembrane.
       0.841
SSA_0203
Conserved hypothetical protein; GC: 44.54%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.728. SignalP prediction: Yes (prob. 0.63); Curator(s): P. Manque, J. Alves; possible transmembrane.
       0.832
SSA_0896
Two-component system, OmpR family, response regulator Irr; GC: 45.36%; Codon Adaptation Index (CAI): 0.8. Curator(s): L. Ozaki, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 
 0.832
SSA_1565
Two-component system, OmpR family, response regulator VicR; GC: 45.58%; Codon Adaptation Index (CAI): 0.814. Curator(s): J. Alves; Protein involved in sensory perception.
 
 
 0.813
SSA_0401
Two-component response transcriptional regulator; GC: 48.75%; Codon Adaptation Index (CAI): 0.789. Curator(s): T. Kitten, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 
 0.807
SSA_1685
Two-component response transcriptional regulator; GC: 45.71%; Codon Adaptation Index (CAI): 0.762. Curator(s): J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
 
 0.797
SSA_1794
Two-component system, OmpR family, manganese sensing response regulator; GC: 48.37%; Codon Adaptation Index (CAI): 0.795. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in sensory perception.
 
 
 0.784
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.