STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0212Phenylalanyl-tRNA synthetase, beta subunit, putative; GC: 47.85%; Codon Adaptation Index (CAI): 0.802. Curator(s): P. Manque; Protein involved in tRNA binding; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (208 aa)    
Predicted Functional Partners:
pheS
Phenylalanyl-tRNA synthetase alpha chain, putative; GC: 48.19%; Codon Adaptation Index (CAI): 0.787. Curator(s): T. Kitten; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
 
 
 0.910
SSA_0210
Conserved hypothetical protein; GC: 47.57%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.751. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): P. Manque.
       0.855
trxA2
Conserved hypothetical protein; GC: 43.75%; Codon Adaptation Index (CAI): 0.757. Curator(s): P. Manque; Protein involved in electron transport and cell redox homeostasis.
       0.855
pepA
Glutamyl aminopeptidase, putative; GC: 52.58%; Codon Adaptation Index (CAI): 0.759. Curator(s): P. Manque; Protein involved in aminopeptidase activity and hydrolase activity.
     
 0.717
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.618
purL
Phosphoribosylformylglycinamidine synthase, putative; GC: 48.7%; Codon Adaptation Index (CAI): 0.782. Curator(s): J. Alves; Protein involved in catalytic activity and ligase activity.
  
  
 0.565
thiI
Thiamine biosynthesis protein, putative; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.507
ssb2
Single-strand DNA-binding protein (conjugal DNA-protein transfer system), putative; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
    0.478
SSA_0809
Translation initiation inhibitor, yjgF family / endoribonuclease L-PSP, putative; GC: 44.36%; Codon Adaptation Index (CAI): 0.797. Highly conserved, active on single-stranded mRNA. Curator(s): X. Ge, J. Alves.
      
 0.471
SSA_2059
16S rRNA uridine-516 pseudouridylate synthase, putative; GC: 48.01%; Codon Adaptation Index (CAI): 0.761. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in pseudouridine synthase activity; Belongs to the pseudouridine synthase RsuA family.
     
 0.455
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.