Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rbsBPeriplasmic sugar-binding protein (ribose porter), putative; GC: 45.49%; Transporter classification TC:3.A.1.2.1. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.762. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.516); Curator(s): P. Manque, J. Alves. (328 aa)    
Predicted Functional Partners:
SSA_0218
Sugar-binding periplasmic protein, putative; GC: 46.65%; Transporter classification TC:3.A.1.1.16. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.787. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque; Protein involved in transport.
 
  
 0.976
SSA_0216
Histidine kinase, putative; GC: 44.98%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.745. Curator(s): P. Manque; Protein involved in protein dimerization activity.
 
    0.961
SSA_0217
Two-component response transcriptional regulator; GC: 46.93%; Codon Adaptation Index (CAI): 0.765. Curator(s): P. Manque, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
 
  
 0.957
SSA_0220
PTS system, mannose-specific IIB component, putative; GC: 45.45%; Transporter classification TC:4.A.6.1.2. Codon Adaptation Index (CAI): 0.79. Curator(s): P. Manque; Protein involved in transferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system.
 
   
 0.880
SSA_1120
Two-component sensor kinase (with C-terminal ATPase domain), putative; GC: 44.25%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.793. SignalP prediction: Yes (prob. 0.513); Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in kinase activity and transferase activity.
  
 
 0.880
SSA_0219
PTS system, sugar-specific enzyme IIA component, putative; GC: 49.54%; Transporter classification TC:4.A.6.1.4. Codon Adaptation Index (CAI): 0.79. Curator(s): P. Manque; Protein involved in transferase activity.
 
   
 0.879
SSA_0221
PTS system, mannose-specific IIC component, putative; GC: 44.92%; Transporter classification TC:4.A.6.1.1. Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.793. SignalP prediction: Yes (prob. 0.878); Curator(s): P. Manque; Protein involved in transferase activity.
 
     0.876
SSA_0222
PTS system, mannose-specific IID component, putative; GC: 45.64%; Transporter classification TC:4.A.6.1.2. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.779. Curator(s): P. Manque; Protein involved in transferase activity.
 
     0.841
SSA_0224
Conserved hypothetical protein; GC: 39.86%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.736. Curator(s): P. Manque.
 
     0.808
ssb2
Single-strand DNA-binding protein (conjugal DNA-protein transfer system), putative; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
       0.660
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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