STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YfkNCyclo-nucleotide phosphodiesterase, putative; GC: 48.96%; Codon Adaptation Index (CAI): 0.761. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque; Protein involved in hydrolase activity, acting on ester bonds. (803 aa)    
Predicted Functional Partners:
deoD
Purine nucleoside phosphorylase, family 1, putative; GC: 44.03%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.783; Protein involved in nucleoside metabolism.
  
 
  0.918
SSA_1311
Hydrolase, haloacid dehalogenase-like family, putative; GC: 45.83%; Codon Adaptation Index (CAI): 0.773; Protein involved in hydrolase activity and metal ion binding.
  
  
  0.911
cdd
Cytidine deaminase, putative; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.910
SSA_0105
Uridine kinase, putative; GC: 47.26%; Codon Adaptation Index (CAI): 0.723. Curator(s): M. Serrano; Protein involved in transferase activity.
     
  0.900
udK
Uridine kinase, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.798. Curator(s): T. Kitten; Protein involved in transferase activity.
     
  0.900
pdp
Pyrimidine nucleoside phosphorylase, putative; GC: 44.37%; Codon Adaptation Index (CAI): 0.805; Protein involved in transferase activity, transferring glycosyl groups.
     
  0.900
punA
Purine nucleoside phosphorylase, putative; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
     
  0.900
SSA_2046
Uridine phosphorylase, putative; GC: 47.06%; Codon Adaptation Index (CAI): 0.772; Protein involved in nucleoside metabolism.
     
  0.900
srtC
Sortase-like protein, putative; GC: 39.86%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.762. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.568); Protein involved in transferase activity.
  
  
 0.669
SSA_0239
7,8-dihydro-8-oxoguanine-triphosphatase, putative; GC: 45.7%; Codon Adaptation Index (CAI): 0.811. Curator(s): P. Manque; Protein involved in hydrolase activity.
 
     0.561
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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