STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0256Metalloregulator ScaR (Fe/Mn-dependent transcriptional repressor), putative; GC: 46.6%; Codon Adaptation Index (CAI): 0.768. Curator(s): P. Manque, J. Alves; Protein involved in regulation of transcription, DNA-dependent. (215 aa)    
Predicted Functional Partners:
ssaB
Manganese/Zinc ABC transporter substrate-binding lipoprotein precursor, putative; GC: 42.37%; Transporter classification TC:3.A.1.15.2. Codon Adaptation Index (CAI): 0.786. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque, J. Alves; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.830
ssaA
ABC-type Mn/Zn transporter, ATP-ase component, putative; GC: 45.47%; Transporter classification TC:3.A.1.15.2. Codon Adaptation Index (CAI): 0.783. Curator(s): P. Manque, J. Alves; Protein involved in nucleoside-triphosphatase activity.
  
  
 0.830
metN
ABC-type methionine transporter, ATPase component, putative; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
    
   0.726
tpx
Thiol peroxidase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.641
ssaC
ABC-type Mn2+/Zn2+ transport systems, permease component, putative; GC: 46.88%; Transporter classification TC:3.A.1.15.2. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.729. Curator(s): P. Manque, J. Alves; Protein involved in ATPase activity, coupled to transmembrane movement of substances.
 
  
 0.576
SSA_0255
Multiple antibiotic resistance operon transcription repressor (MarR), putative; GC: 43.72%; Codon Adaptation Index (CAI): 0.739. Curator(s): P. Manque, J. Alves; Protein involved in regulation of transcription, DNA-dependent.
  
  
 0.548
SSA_0254
Conserved hypothetical protein; GC: 43.43%; Codon Adaptation Index (CAI): 0.751. Curator(s): P. Manque, J. Alves; Protein involved in molecular function unknown; Belongs to the UPF0310 family.
       0.533
nadR
ATPase/kinase, putative; GC: 45.33%; Codon Adaptation Index (CAI): 0.804. Possibly involved in NAD metabolism. Curator(s): J. Alves; Protein involved in nucleotidyltransferase activity and regulation of transcription.
   
    0.510
SSA_0258
Conserved hypothetical protein; GC: 47.27%; Codon Adaptation Index (CAI): 0.787. Curator(s): P. Manque.
     
 0.507
fur
Fe2+/Zn2+ uptake regulation protein, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.786. Curator(s): P. Xu; Protein involved in regulation of transcription, DNA-dependent; Belongs to the Fur family.
  
  
 0.483
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.