Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
pepOZinc metalloproteinase in scaA 5'region, putative; GC: 48.44%; Codon Adaptation Index (CAI): 0.785. Curator(s): P. Manque; Protein involved in metal ion binding and hydrolase activity. (630 aa)    
Predicted Functional Partners:
ssaA
ABC-type Mn/Zn transporter, ATP-ase component, putative; GC: 45.47%; Transporter classification TC:3.A.1.15.2. Codon Adaptation Index (CAI): 0.783. Curator(s): P. Manque, J. Alves; Protein involved in nucleoside-triphosphatase activity.
     
 0.773
ssaB
Manganese/Zinc ABC transporter substrate-binding lipoprotein precursor, putative; GC: 42.37%; Transporter classification TC:3.A.1.15.2. Codon Adaptation Index (CAI): 0.786. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque, J. Alves; Belongs to the bacterial solute-binding protein 9 family.
     
 0.761
pepP
GC: 46.8%; Codon Adaptation Index (CAI): 0.768. Curator(s): M. Chaplin; Protein involved in hydrolase activity; Belongs to the peptidase M24B family.
   
  
 0.734
pepC
Aminopeptidase C, putative; GC: 45.62%; Codon Adaptation Index (CAI): 0.79; Protein involved in hydrolase activity and proteolysis; Belongs to the peptidase C1 family.
  
   
 0.733
pepN
Aminopeptidase N, putative; GC: 45.38%; Codon Adaptation Index (CAI): 0.804. Curator(s): T. Kitten.
 
   
 0.701
kdtB
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
      
 0.695
pepXP
Xaa-Pro dipeptidyl-peptidase, putative; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
      
 0.692
dnaK
Chaperone protein dnaK/HSP70, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.650
pepS
Aminopeptidase PepS, putative; GC: 49.28%; Codon Adaptation Index (CAI): 0.766; Protein involved in hydrolase activity, metabolism and proteolysis.
      
 0.615
pepQ
Proline dipeptidase, putative; GC: 46.17%; Codon Adaptation Index (CAI): 0.806; Protein involved in metalloexopeptidase activity and dipeptidase activity.
   
  
 0.576
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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