STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0293Conserved hypothetical protein; GC: 39.53%; Codon Adaptation Index (CAI): 0.752. Curator(s): P. Manque; Protein involved in lyase activity. (85 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase, putative; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
  
 0.599
SSA_1586
Conserved hypothetical protein; GC: 48.79%; Codon Adaptation Index (CAI): 0.802. Helix-turn-helix prediction: AraC; Protein involved in molecular function unknown and regulation of transcription, DNA-dependent.
 
     0.486
SSA_0294
Hypothetical protein; GC: 36.19%; Codon Adaptation Index (CAI): 0.776. Curator(s): P. Manque.
       0.470
SSA_0320
Membrane protein, putative; GC: 41.89%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.768. SignalP prediction: Yes (prob. 0.536); Curator(s): T. Kitten.
       0.445
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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