STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase, putative; GC: 43.27%; Codon Adaptation Index (CAI): 0.793. Curator(s): P. Manque; Protein involved in transferase activity; Belongs to the phosphoglycerate kinase family. (398 aa)    
Predicted Functional Partners:
gapA
Glyceraldehyde 3-phosphate dehydrogenase, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.806; Protein involved in NAD binding; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.998
tpi
Triosephosphate isomerase, putative; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.997
eno
Enolase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.991
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.986
pgi
Glucose-6-phosphate isomerase, putative; GC: 41.79%; Codon Adaptation Index (CAI): 0.77; Belongs to the GPI family.
  
 
 0.950
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
 
 
 0.942
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, putative; GC: 46.39%; Codon Adaptation Index (CAI): 0.791. Curator(s): X. Ge; Protein involved in oxidoreductase activity; Belongs to the aldehyde dehydrogenase family.
   
 0.934
fba
Fructose-bisphosphate aldolase, putative; GC: 44.33%; Codon Adaptation Index (CAI): 0.763; Protein involved in fructose 1,6-bisphosphate metabolism.
  
 
 0.913
pfk
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
  
 0.760
tkt
Transketolase, putative; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 
 0.752
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.