Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
glnRTranscription regulator (glutamine synthetase repressor), putative; GC: 43.99%; Codon Adaptation Index (CAI): 0.836. Curator(s): T. Kitten, J. Alves; Protein involved in regulation of transcription, DNA-dependent. (121 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase type 1, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.803. Curator(s): T. Kitten; Protein involved in ligase activity; Belongs to the glutamine synthetase family.
 
 
 0.993
SSA_0305
Conserved hypothetical protein; GC: 42.67%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.777. SignalP prediction: Yes (prob. 0.963); Curator(s): T. Kitten.
       0.716
gdhA
NADP-specific glutamate dehydrogenase, putative; GC: 45.88%; Codon Adaptation Index (CAI): 0.789. Curator(s): T. Kitten; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
      
 0.615
SSA_0304
Bacterial cell wall degradation (CHAP/LysM domains), putative; GC: 42.94%; Codon Adaptation Index (CAI): 0.819. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in cell wall catabolism.
  
    0.579
SSA_0308
Conserved hypothetical protein; GC: 39.76%; Codon Adaptation Index (CAI): 0.787. Curator(s): T. Kitten; Protein involved in N-acetyltransferase activity and transferase activity.
       0.568
codY
GTP-sensing transcriptional pleiotropic repressor, putative; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.561
SSA_0313
Conserved uncharacterized protein; GC: 41.13%; Codon Adaptation Index (CAI): 0.813. Highly conserved, but so far Firmicutes specific. Curator(s): T. Kitten, J. Alves; Belongs to the UPF0356 family.
  
 
   0.548
rpoB
DNA-directed RNA polymerase I, beta chain (140 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.512
ccpA
Catabolite control protein A, putative; GC: 43.08%; Codon Adaptation Index (CAI): 0.795. Helix-turn-helix prediction: AraC; Protein involved in regulation of transcription.
      
 0.508
SSA_1903
Conserved hypothetical protein; GC: 47.55%; Codon Adaptation Index (CAI): 0.759.
  
     0.481
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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