STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mvaDDiphosphomevalonate decarboxylase, putative; GC: 47.78%; Codon Adaptation Index (CAI): 0.788. Curator(s): T. Kitten; Protein involved in lyase activity and phosphorylation. (315 aa)    
Predicted Functional Partners:
mvaK2
Phosphomevalonate kinase, putative; GC: 47.55%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.767. Curator(s): T. Kitten; Protein involved in phosphorylation.
 
 
 0.999
fni
Isopentenyl-diphosphate delta-isomerase, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.998
mvaK1
Mevalonate kinase, putative; GC: 49.37%; Codon Adaptation Index (CAI): 0.763. Curator(s): T. Kitten; Protein involved in carbohydrate phosphorylation.
 
  
 0.993
mvaS
Hydroxymethylglutaryl-CoA synthase, putative; GC: 47.16%; Codon Adaptation Index (CAI): 0.76. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in acetyl-CoA metabolism.
 
 
 0.952
ispA
Farnesyl diphosphate synthase, putative; GC: 46.8%; Codon Adaptation Index (CAI): 0.77. Curator(s): P. Xu; Belongs to the FPP/GGPP synthase family.
  
 0.951
mvaA
Hydroxymethylglutaryl-CoA reductase, putative; GC: 50.43%; Codon Adaptation Index (CAI): 0.759. Curator(s): T. Kitten; Protein involved in hydroxymethylglutaryl-CoA reductase activity; Belongs to the HMG-CoA reductase family.
 
  
 0.908
SSA_0332
Conserved hypothetical protein; GC: 47.22%; Codon Adaptation Index (CAI): 0.783. Curator(s): T. Kitten; Protein involved in response to antibiotic.
       0.660
cppA
C3-degrading proteinase, putative; GC: 42.45%; Codon Adaptation Index (CAI): 0.784. Curator(s): T. Kitten.
       0.657
lysS
Lysyl-tRNA synthetase, putative; GC: 44.94%; Codon Adaptation Index (CAI): 0.803; Protein involved in lysyl-tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
    0.597
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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