Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_0341Conserved hypothetical protein; GC: 47.23%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.748. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten. (258 aa)    
Predicted Functional Partners:
SSA_0339
Conserved hypothetical protein; GC: 47.86%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.738. SignalP prediction: Yes (prob. 0.482); Curator(s): T. Kitten.
 
  
 0.968
mvaS
Hydroxymethylglutaryl-CoA synthase, putative; GC: 47.16%; Codon Adaptation Index (CAI): 0.76. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in acetyl-CoA metabolism.
       0.693
mvaA
Hydroxymethylglutaryl-CoA reductase, putative; GC: 50.43%; Codon Adaptation Index (CAI): 0.759. Curator(s): T. Kitten; Protein involved in hydroxymethylglutaryl-CoA reductase activity; Belongs to the HMG-CoA reductase family.
       0.667
SSA_0342
Pyruvate formate-lyase, putative; GC: 44.39%; Codon Adaptation Index (CAI): 0.783. Curator(s): T. Kitten; Protein involved in formate C-acetyltransferase activity and lyase activity.
       0.651
pkn
Serine/threonine protein kinase, putative; GC: 45.95%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.786; Protein involved in transferase activity.
       0.444
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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