STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0342Pyruvate formate-lyase, putative; GC: 44.39%; Codon Adaptation Index (CAI): 0.783. Curator(s): T. Kitten; Protein involved in formate C-acetyltransferase activity and lyase activity. (771 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase, putative; GC: 45.6%; Codon Adaptation Index (CAI): 0.781; Protein involved in transferase activity.
   
 
 0.969
pflA
Pyruvate formate-lyase-activating enzyme, putative; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.961
adhE
Alcohol-acetaldehyde dehydrogenase, putative; GC: 45.69%; Codon Adaptation Index (CAI): 0.794. Curator(s): J. Alves; Protein involved in oxidoreductase activity; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.952
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
   
 
 0.949
ldh
L-lactate dehydrogenase, putative; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.936
spxB
Pyruvate oxidase, putative; GC: 43.3%; Codon Adaptation Index (CAI): 0.777. Curator(s): T. Kitten; Protein involved in thiamin pyrophosphate binding; Belongs to the TPP enzyme family.
     
 0.934
SSA_0523
Aldehyde dehydrogenase, putative; GC: 44.9%; Codon Adaptation Index (CAI): 0.796. Curator(s): D. Akan; Protein involved in oxidoreductase activity.
 
 
 0.933
mvaS
Hydroxymethylglutaryl-CoA synthase, putative; GC: 47.16%; Codon Adaptation Index (CAI): 0.76. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in acetyl-CoA metabolism.
    
  0.930
ilvB
Acetolactate synthase, large subunit, biosynthetic type, putative; GC: 46.27%; Codon Adaptation Index (CAI): 0.799; Protein involved in thiamin pyrophosphate binding.
     
 0.927
acoB
Acetoin dehydrogenase, E1 component, beta subunit, putative; GC: 46.96%; Codon Adaptation Index (CAI): 0.795; Protein involved in acetoin dehydrogenase activity.
   
 
 0.920
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.