| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SSA_0375 | msrB | SSA_0375 | SSA_0374 | Lipoprotein transporter, putative; GC: 41.92%; Transporter classification TC:3.A.1.24.1. Codon Adaptation Index (CAI): 0.79. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Belongs to the nlpA lipoprotein family. | Peptide methionine sulfoxide reductase msrA/msrB, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.547 |
| acoL | grpE | SSA_1174 | SSA_2008 | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | 0.445 |
| acoL | guaB | SSA_1174 | SSA_2374 | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | Inosine-5'-monophosphate dehydrogenase, putative; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.692 |
| acoL | msrA | SSA_1174 | SSA_1118 | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | Peptide methionine sulfoxide reductase, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.675 |
| acoL | msrB | SSA_1174 | SSA_0374 | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | Peptide methionine sulfoxide reductase msrA/msrB, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.675 |
| acoL | nrdH | SSA_1174 | SSA_0771 | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | Glutaredoxin-like protein, putative; GC: 39.27%; Codon Adaptation Index (CAI): 0.804. Involved in electron transport system for ribonucleotide reductase system NrdEF. Curator(s): X. Ge; Protein involved in cell redox homeostasis. | 0.420 |
| acoL | trxA2 | SSA_1174 | SSA_0211 | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | Conserved hypothetical protein; GC: 43.75%; Codon Adaptation Index (CAI): 0.757. Curator(s): P. Manque; Protein involved in electron transport and cell redox homeostasis. | 0.584 |
| basA | msrA | SSA_1523 | SSA_1118 | Glutathione peroxidase, putative; GC: 43.46%; Codon Adaptation Index (CAI): 0.8. Curator(s): J. Alves; Protein involved in oxidoreductase activity; Belongs to the glutathione peroxidase family. | Peptide methionine sulfoxide reductase, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.656 |
| basA | msrB | SSA_1523 | SSA_0374 | Glutathione peroxidase, putative; GC: 43.46%; Codon Adaptation Index (CAI): 0.8. Curator(s): J. Alves; Protein involved in oxidoreductase activity; Belongs to the glutathione peroxidase family. | Peptide methionine sulfoxide reductase msrA/msrB, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.656 |
| basA | nrdH | SSA_1523 | SSA_0771 | Glutathione peroxidase, putative; GC: 43.46%; Codon Adaptation Index (CAI): 0.8. Curator(s): J. Alves; Protein involved in oxidoreductase activity; Belongs to the glutathione peroxidase family. | Glutaredoxin-like protein, putative; GC: 39.27%; Codon Adaptation Index (CAI): 0.804. Involved in electron transport system for ribonucleotide reductase system NrdEF. Curator(s): X. Ge; Protein involved in cell redox homeostasis. | 0.547 |
| basA | trxA2 | SSA_1523 | SSA_0211 | Glutathione peroxidase, putative; GC: 43.46%; Codon Adaptation Index (CAI): 0.8. Curator(s): J. Alves; Protein involved in oxidoreductase activity; Belongs to the glutathione peroxidase family. | Conserved hypothetical protein; GC: 43.75%; Codon Adaptation Index (CAI): 0.757. Curator(s): P. Manque; Protein involved in electron transport and cell redox homeostasis. | 0.566 |
| clpX | grpE | SSA_1093 | SSA_2008 | ATP-dependent Clp protease ATP-binding subunit clpX, putative; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | 0.585 |
| clpX | guaB | SSA_1093 | SSA_2374 | ATP-dependent Clp protease ATP-binding subunit clpX, putative; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Inosine-5'-monophosphate dehydrogenase, putative; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.684 |
| clpX | msrA | SSA_1093 | SSA_1118 | ATP-dependent Clp protease ATP-binding subunit clpX, putative; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Peptide methionine sulfoxide reductase, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.570 |
| clpX | msrB | SSA_1093 | SSA_0374 | ATP-dependent Clp protease ATP-binding subunit clpX, putative; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Peptide methionine sulfoxide reductase msrA/msrB, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.570 |
| grpE | acoL | SSA_2008 | SSA_1174 | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding. | 0.445 |
| grpE | clpX | SSA_2008 | SSA_1093 | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | ATP-dependent Clp protease ATP-binding subunit clpX, putative; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.585 |
| grpE | msrA | SSA_2008 | SSA_1118 | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | Peptide methionine sulfoxide reductase, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.577 |
| grpE | msrB | SSA_2008 | SSA_0374 | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | Peptide methionine sulfoxide reductase msrA/msrB, putative; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.577 |
| grpE | polA | SSA_2008 | SSA_0100 | Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...] | DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.739 |
