Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
SSA_0380Enzyme of poly-gamma-glutamate biosynthesis (capsule formation), putative; GC: 46.71%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.788. Curator(s): T. Kitten, J. Alves. (460 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A, putative; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
    0.588
SSA_0379
PTS system, beta-glucoside-specific EII component, putative; GC: 44.98%; Transporter classification TC:4.A.1.2.6. Transmembrane domains: 11. Codon Adaptation Index (CAI): 0.805. Curator(s): T. Kitten.
     
 0.478
SSA_1782
Conserved hypothetical protein; GC: 45.59%; Codon Adaptation Index (CAI): 0.752; Protein involved in molecular function unknown and hydrolase activity.
     
 0.477
SSA_0390
Conserved hypothetical protein; GC: 47.71%; Codon Adaptation Index (CAI): 0.763. Curator(s): T. Kitten; Protein involved in hydrolase activity, acting on ester bonds.
     
 0.455
SSA_0389
Conserved hypothetical protein; GC: 46.69%; Codon Adaptation Index (CAI): 0.747. Curator(s): T. Kitten; Protein involved in hydrolase activity.
       0.450
SSA_1057
Aminotransferase, class-V, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.745; Protein involved in transaminase activity and transferase activity.
       0.450
thiI
Thiamine biosynthesis protein, putative; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.450
rplU
50S ribosomal protein L21, putative; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.450
rpmA
50S ribosomal protein L27, putative; GC: 45.92%; Codon Adaptation Index (CAI): 0.795; Protein involved in protein biosynthesis; Belongs to the bacterial ribosomal protein bL27 family.
       0.450
SSA_0324
Conserved uncharacterized protein; GC: 46.87%; Codon Adaptation Index (CAI): 0.852. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in regulation of transcription, DNA-dependent.
  
     0.416
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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