Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
opuAbABC transporter, glycine-betaine/proline permease protein, putative; GC: 49.22%; Transporter classification TC:3.A.1.12.5. Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.772. Curator(s): T. Kitten. (574 aa)    
Predicted Functional Partners:
opuAa
Glycine-betaine ABC transporter, ATPase component, putative; GC: 48.53%; Transporter classification TC:3.A.1.12.5. Codon Adaptation Index (CAI): 0.781. Curator(s): T. Kitten; Protein involved in nucleoside-triphosphatase activity.
 
 0.999
SSA_0387
Transcriptional regulator, GntR family, putative; GC: 48.29%; Codon Adaptation Index (CAI): 0.735. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in cation transporter activity.
 
   
 0.934
proW
ABC-type choline transporter, membrane-spanning permease, putative; GC: 43.98%; Transporter classification TC:3.A.1.12.4. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.771. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten.
 
 
0.916
purN
Phosphoribosylglycinamide (GAR) formyltransferase, putative; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
  
 0.810
folK
Bifunctional folate synthesis protein, putative; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
      
 0.635
purM
Phosphoribosylformylglycinamidine cyclo-ligase, putative; GC: 47.31%; Codon Adaptation Index (CAI): 0.795. Curator(s): J. Alves.
   
    0.632
potA
ABC transporter ATP-binding protein-spermidine/putrescine transport, putative; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
    
 0.578
fur
Fe2+/Zn2+ uptake regulation protein, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.786. Curator(s): P. Xu; Protein involved in regulation of transcription, DNA-dependent; Belongs to the Fur family.
     
 0.573
SSA_1359
Arginine/histidine ABC transporter, permease component, putative; GC: 45.55%; Transporter classification TC:3.A.1.3.12. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.786. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves.
   
 
 0.571
SSA_1961
Amino acid ABC transporter, amino acid-binding protein/permease protein, putative; GC: 45.4%; Transporter classification TC:3.A.1.3.12. Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.777. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1).
   
 
 0.571
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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