Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0400Conserved hypothetical protein; GC: 48.09%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.765. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten; beta-lactamase family; Protein involved in response to antibiotic. (593 aa)    
Predicted Functional Partners:
SSA_0332
Conserved hypothetical protein; GC: 47.22%; Codon Adaptation Index (CAI): 0.783. Curator(s): T. Kitten; Protein involved in response to antibiotic.
  
     0.765
SSA_0398
Conserved hypothetical protein; GC: 45.31%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.763. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; beta-lactamase family; Protein involved in response to antibiotic.
 
    
0.735
SSA_0397
Conserved hypothetical protein; GC: 38.14%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.758. Curator(s): T. Kitten.
       0.697
SSA_0396
Conserved hypothetical protein; GC: 45.15%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.77. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.528); Curator(s): T. Kitten; Protein involved in hydrolase activity.
 
     0.529
SSA_0401
Two-component response transcriptional regulator; GC: 48.75%; Codon Adaptation Index (CAI): 0.789. Curator(s): T. Kitten, J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
       0.444
SSA_0402
Histidine kinase, putative; GC: 48.4%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.769. SignalP prediction: Yes (prob. 0.46); Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in transferase activity, transferring phosphorus-containing groups and kinase activity.
       0.444
SSA_1065
Beta-hexosamidase A, putative; GC: 45.47%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.766. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in hydrolase activity, acting on glycosyl bonds, hydrolase activity and carbohydrate metabolism.
 
  
 0.404
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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