STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hutHHistidine ammonia-lyase, putative; GC: 48.1%; Codon Adaptation Index (CAI): 0.784. Curator(s): M. Chaplin; Protein involved in lyase activity; Belongs to the PAL/histidase family. (516 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase, putative; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
Imidazolonepropionase, putative; GC: 49.13%; Codon Adaptation Index (CAI): 0.785. Curator(s): M. Chaplin; Protein involved in imidazolonepropionase activity; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.994
hisD
Histidinol dehydrogenase, putative; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.922
hutG
Formimidoylglutamase, putative; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
  
 0.906
SSA_0431
Conserved hypothetical protein; GC: 47%; Codon Adaptation Index (CAI): 0.712. Curator(s): M. Chaplin.
 
  
 0.857
fhs1
Formate--tetrahydrofolate ligase, putative; GC: 48.06%; Codon Adaptation Index (CAI): 0.797. Curator(s): M. Chaplin; Protein involved in ligase activity and folic acid and derivative biosynthesis.
     
 0.824
SSA_0430
Cationic amino acid transporter, putative; GC: 42.72%; Transporter classification TC:2.A.3.6.1. Transmembrane domains: 12. Codon Adaptation Index (CAI): 0.757. Curator(s): M. Chaplin, J. Alves.
     
 0.798
SSA_0433
Methenyl tetrahydrofolate cyclohydrolase, putative; GC: 49.12%; Codon Adaptation Index (CAI): 0.792. Curator(s): M. Chaplin.
  
  
 0.796
SSA_0434
Glutamate formiminotransferase, putative; GC: 47.11%; Codon Adaptation Index (CAI): 0.796. Curator(s): M. Chaplin.
 
    0.765
SSA_1144
Beta-N-acetylhexosaminidase, putative; GC: 42.05%; Codon Adaptation Index (CAI): 0.789; Protein involved in hydrolase activity, carbohydrate metabolism and cell adhesion.
   
    0.592
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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