STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0441Conserved hypothetical protein; GC: 40.16%; Codon Adaptation Index (CAI): 0.793. Helix-turn-helix prediction: AraC. Curator(s): M. Chaplin; Protein involved in regulation of transcription. (204 aa)    
Predicted Functional Partners:
SSA_0443
Possible ABC-type efflux pump permease component, putative; GC: 41.28%; Transmembrane domains: 12. Codon Adaptation Index (CAI): 0.726. Curator(s): M. Chaplin, J. Alves.
 
     0.702
SSA_0310
Conserved hypothetical protein; GC: 40.14%; Codon Adaptation Index (CAI): 0.782. Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in regulation of transcription and regulation of transcription, DNA-dependent.
  
     0.662
mefE
Macrolide-efflux protein, putative; GC: 45.79%; Transporter classification TC:2.A.1.21.1. Transmembrane domains: 12. Codon Adaptation Index (CAI): 0.759. Curator(s): D. Akan, J. Alves.
  
     0.581
SSA_0442
ABC-type multidrug transport system, ATPase component, putative; GC: 40.62%; Transporter classification TC:3.A.1.211.3. Codon Adaptation Index (CAI): 0.727. Curator(s): M. Chaplin, J. Alves; Protein involved in nucleoside-triphosphatase activity.
 
     0.556
rpsR
30S ribosomal protein S18, putative; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.531
SSA_0445
Hypothetical protein; GC: 37.14%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.721. SignalP prediction: Yes (prob. 0.999); Curator(s): M. Chaplin.
       0.482
ssb
Single-strand binding protein, putative; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
    0.457
SSA_0607
ABC transporter, permease component, putative; GC: 46.94%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.754. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): D. Akan, J. Alves.
 
     0.457
rpsF
30S ribosomal protein S6, putative; Binds together with S18 to 16S ribosomal RNA.
       0.444
SSA_1670
Transcriptional regulator, TetR/AcrR family, putative; GC: 41.83%; Codon Adaptation Index (CAI): 0.772. Helix-turn-helix prediction: AraC. Curator(s): J. Alves; Protein involved in regulation of transcription.
  
     0.412
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.