STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0458Formylmethionine deformylase, putative; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (136 aa)    
Predicted Functional Partners:
rplV
50S ribosomal protein L22, putative; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
    
   0.788
scrK
Fructokinase, putative; GC: 47.78%; Codon Adaptation Index (CAI): 0.801. Curator(s): M. Chaplin; Protein involved in fructokinase activity and kinase activity.
       0.774
rplQ
50S ribosomal protein L17, putative; GC: 43.41%; Codon Adaptation Index (CAI): 0.826. Curator(s): M. Serrano; Protein involved in protein biosynthesis.
   
   0.758
rplU
50S ribosomal protein L21, putative; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 0.736
rpsF
30S ribosomal protein S6, putative; Binds together with S18 to 16S ribosomal RNA.
   
   0.731
ropA
Trigger factor, putative; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
 
 0.723
rplD
50S ribosomal protein L4, putative; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
    
   0.717
rpsU
Ribosomal protein S21, putative; GC: 37.85%; Codon Adaptation Index (CAI): 0.833. Curator(s): L. Ozaki; Belongs to the bacterial ribosomal protein bS21 family.
  
 
 0.700
rplM
50S ribosomal protein L13, putative; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.690
rpmB
50S ribosomal protein L28, putative; GC: 39.68%; Codon Adaptation Index (CAI): 0.837; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.688
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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