STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
cobQ-2Cobyric acid synthase, putative; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (499 aa)    
Predicted Functional Partners:
SSA_0472
Precorrin-3B C17-methyltransferase, putative; GC: 44.9%; Codon Adaptation Index (CAI): 0.78. Curator(s): M. Chaplin; Protein involved in precorrin-3B C17-methyltransferase activity.
  
 0.989
cobD
Cobalamin biosynthesis protein cobD, putative; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.988
cobU
Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase, putative; GC: 53.5%; Codon Adaptation Index (CAI): 0.765. Curator(s): M. Chaplin, J. Alves; Protein involved in nucleotidyltransferase activity.
  
 0.987
SSA_0482
ATP:cobalamin adenosyl transferase, putative; GC: 50.87%; Codon Adaptation Index (CAI): 0.746. Curator(s): M. Chaplin; Protein involved in transferase activity; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.984
cbiA
Cobyrinic acid A,C-diamide synthase, putative; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.974
cobS
Cobalamin 5'-phosphate synthase, putative; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.967
SSA_0476
Precorrin-2 C20-methyltransferase, putative; GC: 49.29%; Codon Adaptation Index (CAI): 0.778. Curator(s): M. Chaplin; Protein involved in S-adenosylmethionine-dependent methyltransferase activity, transferase activity and precorrin-2 C20-methyltransferase activity.
 
  
 0.965
SSA_0510
L-threonine-O-3-phosphate decarboxylase, putative; GC: 48.58%; Codon Adaptation Index (CAI): 0.77. Curator(s): D. Akan.
  
 0.961
SSA_0473
Precorrin-6x reductase, putative; GC: 51.6%; Codon Adaptation Index (CAI): 0.768. Curator(s): M. Chaplin; Protein involved in precorrin-6A reductase activity.
 
  
 0.959
cobL
Precorrin-6B methylase 2,putative; GC: 51.23%; Codon Adaptation Index (CAI): 0.757. Curator(s): M. Chaplin, J. Alves; Protein involved in transferase activity and S-adenosylmethionine-dependent methyltransferase activity.
 
  
 0.950
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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