STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0482ATP:cobalamin adenosyl transferase, putative; GC: 50.87%; Codon Adaptation Index (CAI): 0.746. Curator(s): M. Chaplin; Protein involved in transferase activity; Belongs to the Cob(I)alamin adenosyltransferase family. (191 aa)    
Predicted Functional Partners:
cobQ-2
Cobyric acid synthase, putative; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
    
 0.984
cobU
Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase, putative; GC: 53.5%; Codon Adaptation Index (CAI): 0.765. Curator(s): M. Chaplin, J. Alves; Protein involved in nucleotidyltransferase activity.
    
 0.962
cobS
Cobalamin 5'-phosphate synthase, putative; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
 0.961
cobD
Cobalamin biosynthesis protein cobD, putative; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
 0.929
cbiA
Cobyrinic acid A,C-diamide synthase, putative; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
    
 0.926
SSA_0513
ATP:cob(I)alamin adenosyltransferase, putative; GC: 45.17%; Codon Adaptation Index (CAI): 0.781. Curator(s): D. Akan; Protein involved in transferase activity; Belongs to the Cob(I)alamin adenosyltransferase family.
  
  
 
0.905
SSA_0483
Siroheme synthase, putative; GC: 50.46%; Codon Adaptation Index (CAI): 0.724. Curator(s): M. Chaplin; Protein involved in NAD binding.
     
 0.842
SSA_0480
Cobalt ABC transporter, ATP-binding protein, putative; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
     
 0.822
pduO
PduO protein, putative; GC: 46.67%; Codon Adaptation Index (CAI): 0.776. Curator(s): D. Akan.
    
 0.777
hemA
Glutamyl-tRNA reductase, putative; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.745
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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