Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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cobSCobalamin 5'-phosphate synthase, putative; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (242 aa)    
Predicted Functional Partners:
cobU
Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase, putative; GC: 53.5%; Codon Adaptation Index (CAI): 0.765. Curator(s): M. Chaplin, J. Alves; Protein involved in nucleotidyltransferase activity.
 
 
 0.997
SSA_0491
Alpha-ribazole-5'-phosphate phosphatase, putative; GC: 51.31%; Codon Adaptation Index (CAI): 0.754. Curator(s): M. Chaplin; Belongs to the phosphoglycerate mutase family.
 
 
 0.986
cobQ-2
Cobyric acid synthase, putative; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.967
SSA_0482
ATP:cobalamin adenosyl transferase, putative; GC: 50.87%; Codon Adaptation Index (CAI): 0.746. Curator(s): M. Chaplin; Protein involved in transferase activity; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.961
SSA_0512
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, putative; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.951
SSA_0472
Precorrin-3B C17-methyltransferase, putative; GC: 44.9%; Codon Adaptation Index (CAI): 0.78. Curator(s): M. Chaplin; Protein involved in precorrin-3B C17-methyltransferase activity.
 
  
 0.938
SSA_0513
ATP:cob(I)alamin adenosyltransferase, putative; GC: 45.17%; Codon Adaptation Index (CAI): 0.781. Curator(s): D. Akan; Protein involved in transferase activity; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.912
cobD
Cobalamin biosynthesis protein cobD, putative; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.878
hemL
Glutamate-1-semialdehyde 2,1-aminotransferase, putative; GC: 51.27%; Codon Adaptation Index (CAI): 0.772. Curator(s): M. Chaplin, T. Kitten; Protein involved in glutamate-1-semialdehyde 2,1-aminomutase activity.
     
 0.850
cbiA
Cobyrinic acid A,C-diamide synthase, putative; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.847
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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