STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_0540Glycerol uptake facilitator protein, putative; GC: 48.88%; Transporter classification TC:1.A.8.2.1. Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.745. Curator(s): D. Akan; Belongs to the MIP/aquaporin (TC 1.A.8) family. (237 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase, putative; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.719
glp
Alpha-glycerophosphate oxidase, putative; GC: 48.17%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.769. SignalP prediction: Yes (prob. 0.943).
 
  
 0.681
dnaJ
Chaperone protein dnaJ, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]
    
 
 0.590
pduO
PduO protein, putative; GC: 46.67%; Codon Adaptation Index (CAI): 0.776. Curator(s): D. Akan.
     
 0.576
pppL
Phosphoprotein phosphatase, putative; GC: 43.99%; Codon Adaptation Index (CAI): 0.817; Protein involved in catalytic activity.
    
   0.565
fruA
PTS system, fructose specific II ABC components, putative; GC: 43.96%; Transporter classification TC:4.A.2.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.786.
   
  
 0.548
SSA_0066
Conserved hypothetical protein; GC: 44.2%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.79. Curator(s): J. Alves.
    
 
 0.532
ackA-2
Acetate kinase, putative; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.522
ppiA
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, putative; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.488
ugpQ
Membrane-anchored glycerophosphoryl diester phosphodiesterase, putative; GC: 44.84%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.752. SignalP prediction: Yes (prob. 0.982); Curator(s): T. Kitten, J. Alves; Protein involved in glycerophosphodiester phosphodiesterase activity.
  
 
 0.466
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.