STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_0576Conserved GTPase, putative; GC: 48.15%; Codon Adaptation Index (CAI): 0.803. Curator(s): D. Akan, J. Alves; Protein involved in GTP binding. (368 aa)    
Predicted Functional Partners:
rsfS
Conserved uncharacterized protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
 
 0.944
SSA_0575
Hydrolase, HAD superfamily, putative; GC: 45.69%; Codon Adaptation Index (CAI): 0.762. Curator(s): D. Akan; Protein involved in metabolism.
 
  
 0.923
SSA_0577
Ancient RNA-binding IF3-C fold (CRS1/YhbY domain), putative; GC: 44.23%; Codon Adaptation Index (CAI): 0.77. Curator(s): D. Akan, J. Alves; Protein involved in molecular function unknown.
  
  
 0.898
aroE
Shikimate dehydrogenase, putative; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
   0.898
nadD
Nicotinate-nucleotide adenylyltransferase, putative; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.876
SSA_0579
Hydrolase, HAD superfamily, putative; GC: 49.5%; Codon Adaptation Index (CAI): 0.731. Curator(s): D. Akan; Protein involved in catalytic activity.
  
  
 0.851
rplJ
50S ribosomal protein L10, putative; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.844
rpmD
50S ribosomal protein L30, putative; GC: 38.8%; Codon Adaptation Index (CAI): 0.819. Curator(s): M. Serrano.
   
 
 0.836
rplX
50S ribosomal protein L24, putative; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
   0.802
rplD
50S ribosomal protein L4, putative; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
   0.799
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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